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The Role of the Key Effector of Necroptotic Cell Death, MLKL, in Mouse Models of Disease
Necroptosis is an inflammatory form of lytic programmed cell death that is thought to have evolved to defend against pathogens. Genetic deletion of the terminal effector protein—MLKL—shows no overt phenotype in the C57BL/6 mouse strain under conventional laboratory housing conditions. Small molecule...
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| Publicado no: | Biomolecules |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8227991/ https://ncbi.nlm.nih.gov/pubmed/34071602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11060803 |
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