Nuclear TRAF3 is a negative regulator of CREB in B cells

The adaptor protein TNF receptor-associated factor 3 (TRAF3) regulates signaling through B-lymphocyte receptors, including CD40, BAFF receptor, and Toll-like receptors, and also plays a critical role inhibiting B-cell homoeostatic survival. Consistent with these findings, loss-of-function human TRAF...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Mambetsariev, Nurbek, Lin, Wai W., Stunz, Laura L., Hanson, Brett M., Hildebrand, Joanne M., Bishop, Gail A.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2016
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4743771/
https://ncbi.nlm.nih.gov/pubmed/26755589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1514586113
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