The oncogenic membrane protein LMP1 sequesters TRAF3 in B-cell lymphoma cells to produce functional TRAF3 deficiency

Loss-of-function mutations in genes encoding the signaling protein tumor necrosis factor receptor–associated factor 3 (TRAF3) are commonly found in human B-cell malignancies, especially multiple myeloma and B-cell lymphoma (BCL). B-cell TRAF3 deficiency results in enhanced cell survival, elevated ac...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Blood Adv
Hauptverfasser: Bangalore-Prakash, Pradeep, Stunz, Laura L., Mambetsariev, Nurbek, Whillock, Amy L., Hostager, Bruce S., Bishop, Gail A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2017
Schlagworte:
Immunobiology and Immunotherapy
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5745131/
https://ncbi.nlm.nih.gov/pubmed/29296923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017009670
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge