The oncogenic membrane protein LMP1 sequesters TRAF3 in B-cell lymphoma cells to produce functional TRAF3 deficiency

Loss-of-function mutations in genes encoding the signaling protein tumor necrosis factor receptor–associated factor 3 (TRAF3) are commonly found in human B-cell malignancies, especially multiple myeloma and B-cell lymphoma (BCL). B-cell TRAF3 deficiency results in enhanced cell survival, elevated ac...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Blood Adv
मुख्य लेखकों: Bangalore-Prakash, Pradeep, Stunz, Laura L., Mambetsariev, Nurbek, Whillock, Amy L., Hostager, Bruce S., Bishop, Gail A.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society of Hematology 2017
विषय:
Immunobiology and Immunotherapy
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5745131/
https://ncbi.nlm.nih.gov/pubmed/29296923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017009670
टैग : टैग जोड़ें
कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!

समान संसाधन