It's not over until the FAT lady sings

Por Herold, Marco J, Strasser, Andreas
Publicado em 2014

A1/Bfl-1 in leukocyte development and cell death

Por Ottina, Eleonora, Tischner, Denise, Herold, Marco J., Villunger, Andreas
Publicado em 2012

Inducible and reversible gene silencing by stable integration of an shRNA-encoding lentivirus in transgenic rats

Por Herold, Marco J., van den Brandt, Jens, Seibler, Jost, Reichardt, Holger M.
Publicado em 2008

Glucocorticoids exert opposing effects on macrophage function dependent on their concentration

Por Lim, Hee-Young, Müller, Nora, Herold, Marco J, van den Brandt, Jens, Reichardt, Holger M
Publicado em 2007

Clearance of Measles Virus from Persistently Infected Cells by Short Hairpin RNA

Por Zinke, Michael, Kendl, Sabine, Singethan, Katrin, Fehrholz, Markus, Reuter, Dajana, Rennick, Linda, Herold, Marco J., Schneider-Schaulies, Jürgen
Publicado em 2009

Male sterility in Mcl-1-flox mice is not due to enhanced Mcl1 protein stability

Por Ah-Cann, Casey, Tailler, Maximilien, Kueh, Andrew J, Herold, Marco J, Opferman, Joseph T, Asselin-Labat, Marie-Liesse, Bouillet, Philippe
Publicado no Cell Death Dis (2016)

Targeting antiapoptotic A1/Bfl-1 by in vivo RNAi reveals multiple roles in leukocyte development in mice

Por Ottina, Eleonora, Grespi, Francesca, Tischner, Denise, Soratroi, Claudia, Geley, Stephan, Ploner, Andreas, Reichardt, Holger M., Villunger, Andreas, Herold, Marco J.
Publicado em 2012

The BH3-only proteins Bim and Puma cooperate to impose deletional T-cell tolerance to organ-specific antigens

Por Gray, Daniel H. D., Kupresanin, Fiona, Berzins, Stuart P., Herold, Marco J., O’Reilly, Lorraine A., Bouillet, Philippe, Strasser, Andreas
Publicado em 2012

Foxo-mediated Bim transcription is dispensable for the apoptosis of hematopoietic cells that is mediated by this BH3-only protein

Por Herold, Marco J, Rohrbeck, Leona, Lang, Mathias J, Grumont, Raelene, Gerondakis, Steve, Tai, Lin, Bouillet, Philippe, Kaufmann, Thomas, Strasser, Andreas
Publicado em 2013

PEGylation of interferon α2 improves lymphatic exposure after subcutaneous and intravenous administration and improves antitumour efficacy against lymphatic breast cancer metastase...

Por Kaminskas, Lisa M, Ascher, David B, McLeod, Victoria M, Herold, Marco J, Le, Caroline P, Sloan, Erica K, Porter, Christopher JH
Publicado em 2013

RAG-induced DNA lesions activate proapoptotic BIM to suppress lymphomagenesis in p53-deficient mice

Por Delbridge, Alex R.D., Pang, Swee Heng Milon, Vandenberg, Cassandra J., Grabow, Stephanie, Aubrey, Brandon J., Tai, Lin, Herold, Marco J., Strasser, Andreas
Publicado no J Exp Med (2016)

The BCL-2 pro-survival protein A1 is dispensable for T cell homeostasis on viral infection

Por Tuzlak, Selma, Schenk, Robyn L, Vasanthakumar, Ajithkumar, Preston, Simon P, Haschka, Manuel D, Zotos, Dimitra, Kallies, Axel, Strasser, Andreas, Villunger, Andreas, Herold, Marco J
Publicado no Cell Death Differ (2017)

Mutually exclusive regulation of T cell survival by IL-7R and antigen receptor-induced signals

Por Koenen, Paul, Heinzel, Susanne, Carrington, Emma M., Happo, Lina, Alexander, Warren S., Zhang, Jian-Guo, Herold, Marco J., Scott, Clare L., Lew, Andrew M., Strasser, Andreas, Hodgkin, Philip D.
Publicado em 2013

Hepatocyte growth factor renders BRAF mutant human melanoma cell lines resistant to PLX4032 by downregulating the pro-apoptotic BH3-only proteins PUMA and BIM

Por Rohrbeck, Leona, Gong, Jia-Nan, Lee, Erinna F, Kueh, Andrew J, Behren, Andreas, Tai, Lin, Lessene, Guillaume, Huang, David C S, Fairlie, Walter D, Strasser, Andreas, Herold, Marco J
Publicado no Cell Death Differ (2016)

Characterisation of mice lacking all functional isoforms of the pro-survival BCL-2 family member A1 reveals minor defects in the haematopoietic compartment

Por Schenk, Robyn L, Tuzlak, Selma, Carrington, Emma M, Zhan, Yifan, Heinzel, Susanne, Teh, Charis E, Gray, Daniel H, Tai, Lin, Lew, Andrew M, Villunger, Andreas, Strasser, Andreas, Herold, Marco J
Publicado no Cell Death Differ (2017)

Maximal killing of lymphoma cells by DNA damage–inducing therapy requires not only the p53 targets Puma and Noxa, but also Bim

Por Happo, Lina, Cragg, Mark S., Phipson, Belinda, Haga, Jon M., Jansen, Elisa S., Herold, Marco J., Dewson, Grant, Michalak, Ewa M., Vandenberg, Cassandra J., Smyth, Gordon K., Strasser, Andreas, Cory, Suzanne, Scott, Clare L.
Publicado em 2010

Myeloid-derived suppressor activity is mediated by monocytic lineages maintained by continuous inhibition of extrinsic and intrinsic death pathways

Por Haverkamp, Jessica M., Smith, Amber M., Weinlich, Ricardo, Dillon, Christopher P., Qualls, Joseph E., Neale, Geoffrey, Koss, Brian, Kim, Young, Bronte, Vincenzo, Herold, Marco J., Green, Douglas R., Opferman, Joseph T., Murray, Peter J.
Publicado no Immunity (2014)

Apoptotic Caspases Suppress mtDNA-Induced STING-Mediated Type I IFN Production

Por White, Michael J., McArthur, Kate, Metcalf, Donald, Lane, Rachael M., Cambier, John C., Herold, Marco J., van Delft, Mark F., Bedoui, Sammy, Lessene, Guillaume, Ritchie, Matthew E., Huang, David C.S., Kile, Benjamin T.
Publicado no Cell (2014)

Anti-apoptotic Mcl-1 is essential for the development and sustained growth of acute myeloid leukemia

Por Glaser, Stefan P., Lee, Erinna F., Trounson, Evelyn, Bouillet, Philippe, Wei, Andrew, Fairlie, W. Douglas, Izon, David J., Zuber, Johannes, Rappaport, Amy R., Herold, Marco J., Alexander, Warren S., Lowe, Scott W., Robb, Lorraine, Strasser, Andreas
Publicado em 2012

Targeting of MCL-1 kills MYC-driven mouse and human lymphomas even when they bear mutations in p53

Por Kelly, Gemma L., Grabow, Stephanie, Glaser, Stefan P., Fitzsimmons, Leah, Aubrey, Brandon J., Okamoto, Toru, Valente, Liz J., Robati, Mikara, Tai, Lin, Fairlie, W. Douglas, Lee, Erinna F., Lindstrom, Mikael S., Wiman, Klas G., Huang, David C.S., Bouillet, Philippe, Rowe, Martin, Rickinson, Alan B., Herold, Marco J., Strasser, Andreas
Publicado em 2014