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MARCH1-mediated ubiquitination of MHC II impacts the MHC I antigen presentation pathway
Major histocompatibility complex class II (MHC II) expression and turn-over are regulated via its ubiquitination by the membrane associated RING-CH 1 (MARCH1) E3 ligase. Unexpectedly, we show that MHC II ubiquitination also impacts MHC I. Lack of MARCH1 in B cells and dendritic cells (DCs) resulted...
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| 出版年: | PLoS One |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2018
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6042767/ https://ncbi.nlm.nih.gov/pubmed/30001419 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0200540 |
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