Anti-apoptotic A1 is not essential for lymphoma development in Eµ-Myc mice but helps sustain transplanted Eµ-Myc tumour cells

The transcription factor c-MYC regulates a multiplicity of genes involved in cellular growth, proliferation, metabolism and DNA damage response and its overexpression is a hallmark of many tumours. Since MYC promotes apoptosis under conditions of stress, such as limited availability of nutrients or...

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Pubblicato in:Cell Death Differ
Autori principali: Mensink, Mark, Anstee, Natasha S., Robati, Mikara, Schenk, Robyn L., Herold, Marco J., Cory, Suzanne, Vandenberg, Cassandra J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5864240/
https://ncbi.nlm.nih.gov/pubmed/29339775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-017-0045-8
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