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Characterisation of mice lacking the inflammatory caspases-1/11/12 reveals no contribution of caspase-12 to cell death and sepsis

Caspases exert critical functions in diverse cell death pathways, including apoptosis and pyroptosis, but some caspases also have roles in the processing of cytokines into their functional forms during inflammation. The roles of many caspases have been unravelled by the generation of knockout mice,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cell Death Differ
Hauptverfasser: Salvamoser, Ranja, Brinkmann, Kerstin, O’Reilly, Lorraine A., Whitehead, Lachlan, Strasser, Andreas, Herold, Marco J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6748106/
https://ncbi.nlm.nih.gov/pubmed/30154447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-018-0188-2
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