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Characterisation of mice lacking the inflammatory caspases-1/11/12 reveals no contribution of caspase-12 to cell death and sepsis

Caspases exert critical functions in diverse cell death pathways, including apoptosis and pyroptosis, but some caspases also have roles in the processing of cytokines into their functional forms during inflammation. The roles of many caspases have been unravelled by the generation of knockout mice,...

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Bibliografiske detaljer
Udgivet i:Cell Death Differ
Main Authors: Salvamoser, Ranja, Brinkmann, Kerstin, O’Reilly, Lorraine A., Whitehead, Lachlan, Strasser, Andreas, Herold, Marco J.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6748106/
https://ncbi.nlm.nih.gov/pubmed/30154447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-018-0188-2
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