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Improved emergency myelopoiesis and survival in neonatal sepsis by caspase-1/11 ablation

Over one million newborns die annually from sepsis with the highest mortality in premature and low-birthweight infants. The inflammasome plays a central role in the regulation of innate immunity and inflammation, and is presumed to be involved in protective immunity, in large part through the caspas...

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Detalhes bibliográficos
Publicado no:Immunology
Main Authors: Gentile, Lori F, Cuenca, Angela L, Cuenca, Alex G, Nacionales, Dina C, Ungaro, Ricardo, Efron, Philip A, Moldawer, Lyle L, Larson, Shawn D
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4427394/
https://ncbi.nlm.nih.gov/pubmed/25684123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12450
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