Aluminum Adjuvant Improves Survival via NLRP3 Inflammasome and Myeloid Non-Granulocytic Cells in a Murine Model of Neonatal Sepsis

Neonatal sepsis leads to significant morbidity and mortality with the highest risk of death occurring in preterm (<37 weeks) and low birth weight (LBW; <2500g) infants. The neonatal immune system is developmentally immature with well described defects in innate and adaptive immune responses. I...

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Veröffentlicht in:Shock
Hauptverfasser: Rincon, Jaimar C, Hawkins, Russell B, Hollen, Mckenzie, Nacionales, Dina C, Ungaro, Ricardo, Efron, Philip A, Moldawer, Lyle L, Larson, Shawn D
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8025597/
https://ncbi.nlm.nih.gov/pubmed/32769820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000001623
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