Protective Immunity and Defects in the Neonatal and Elderly Immune Response to Sepsis

Populations encompassing extremes of age, including neonates and elderly, have greater mortality from sepsis. We propose that the increased mortality observed in the neonatal and elderly populations after sepsis is due to fundamental differences in host protective immunity, and are manifested at the...

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Detalhes bibliográficos
Main Authors: Gentile, Lori F., Nacionales, Dina C., Lopez, M. Cecilia, Vanzant, Erin, Cuenca, Angela, Cuenca, Alex G., Ungaro, Ricardo, Szpila, Ben E., Larson, Shawn, Joseph, Anna, Moore, Frederick, Leeuwenburgh, Christiaan, Baker, Henry V., Moldawer, Lyle L., Efron, Philip A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3967513/
https://ncbi.nlm.nih.gov/pubmed/24591376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301726
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