A toolbox for imaging RIPK1, RIPK3, and MLKL in mouse and human cells

Necroptosis is a lytic, inflammatory cell death pathway that is dysregulated in many human pathologies. The pathway is executed by a core machinery comprising the RIPK1 and RIPK3 kinases, which assemble into necrosomes in the cytoplasm, and the terminal effector pseudokinase, MLKL. RIPK3-mediated ph...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cell Death Differ
Päätekijät: Samson, André L., Fitzgibbon, Cheree, Patel, Komal M., Hildebrand, Joanne M., Whitehead, Lachlan W., Rimes, Joel S., Jacobsen, Annette V., Horne, Christopher R., Gavin, Xavier J., Young, Samuel N., Rogers, Kelly L., Hawkins, Edwin D., Murphy, James M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2021
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8257593/
https://ncbi.nlm.nih.gov/pubmed/33589776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-021-00742-x
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