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Necroptosis induced by RIPK3 requires MLKL but not Drp1
Necroptosis is a mechanism by which cells can kill themselves that does not require caspase activity or the presence of the pro-apoptotic Bcl-2 family members Bax or Bak. It has been reported that RIPK3 (receptor interacting protein kinase 3) activates MLKL (mixed lineage kinase domain-like) to caus...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3944236/ https://ncbi.nlm.nih.gov/pubmed/24577084 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.18 |
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