Necroptosis induced by RIPK3 requires MLKL but not Drp1

Necroptosis is a mechanism by which cells can kill themselves that does not require caspase activity or the presence of the pro-apoptotic Bcl-2 family members Bax or Bak. It has been reported that RIPK3 (receptor interacting protein kinase 3) activates MLKL (mixed lineage kinase domain-like) to caus...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Moujalled, D M, Cook, W D, Murphy, J M, Vaux, D L
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2014
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944236/
https://ncbi.nlm.nih.gov/pubmed/24577084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.18
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker