RIPK1- and RIPK3-induced cell death mode is determined by target availability

Both receptor-interacting protein kinase 1 (RIPK1) and RIPK3 can signal cell death following death receptor ligation. To study the requirements for RIPK-triggered cell death in the absence of death receptor signaling, we engineered inducible versions of RIPK1 and RIPK3 that can be activated by dimer...

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Bibliografiske detaljer
Main Authors: Cook, W D, Moujalled, D M, Ralph, T J, Lock, P, Young, S N, Murphy, J M, Vaux, D L
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2014
Fag:
Original Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4158685/
https://ncbi.nlm.nih.gov/pubmed/24902899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2014.70
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