RIPK1 protects hepatocytes from death in Fas-induced hepatitis

Hepatocyte death is a central event during liver disease progression, in which immune cells play key roles by activating members of the Tumor Necrosis Factor Receptor Superfamily (TNFRSF), including TNFR1 (TNFRSF1A), Fas (TNFRSF6) and TRAIL-R2 (TNFRSF10B). Receptor Interacting Protein Kinase 1 (RIPK...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Filliol, Aveline, Farooq, Muhammad, Piquet-Pellorce, Claire, Genet, Valentine, Dimanche-Boitrel, Marie-Thérèse, Vandenabeele, Peter, Bertrand, Mathieu J. M., Samson, Michel, Le Seyec, Jacques
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5569041/
https://ncbi.nlm.nih.gov/pubmed/28835677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09789-8
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