TRAIL induces necroptosis involving RIPK1/RIPK3-dependent PARP-1 activation

Although TRAIL (tumor necrosis factor (TNF)-related apoptosis inducing ligand) is a well-known apoptosis inducer, we have previously demonstrated that acidic extracellular pH (pHe) switches TRAIL-induced apoptosis to regulated necrosis (or necroptosis) in human HT29 colon and HepG2 liver cancer cell...

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Detalhes bibliográficos
Main Authors: Jouan-Lanhouet, S, Arshad, M I, Piquet-Pellorce, C, Martin-Chouly, C, Le Moigne-Muller, G, Van Herreweghe, F, Takahashi, N, Sergent, O, Lagadic-Gossmann, D, Vandenabeele, P, Samson, M, Dimanche-Boitrel, M-T
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504714/
https://ncbi.nlm.nih.gov/pubmed/22814620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2012.90
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