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Is SIRT2 required for necroptosis?
Sirtuins can promote deacetylation of a wide range of substrates in diverse cellular compartments and regulate many cellular processes(1,2). Recently Narayan et al., reported that SIRT2 was required for necroptosis based on their findings that SIRT2 inhibition, knock-down or knock-out prevented necr...
में बचाया:
मुख्य लेखकों: | , , , , , , , , , , , , , , , , , |
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स्वरूप: | Artigo |
भाषा: | Inglês |
प्रकाशित: |
2014
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विषय: | |
ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4005920/ https://ncbi.nlm.nih.gov/pubmed/24572428 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13024 |
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