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Complex Pathologic Roles of RIPK1 and RIPK3: Moving Beyond Necroptosis

A process of regulated necrosis, termed necroptosis, has been recognized as a major contributor to cell death and inflammation occurring under a wide range of pathologic settings. The core event in necroptosis is the formation of the detergent-insoluble “necrosome” complex of homologous Ser/Thr kina...

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Vydáno v:Trends Pharmacol Sci
Hlavní autoři: Wegner, Kelby W., Saleh, Danish, Degterev, Alexei
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325808/
https://ncbi.nlm.nih.gov/pubmed/28126382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2016.12.005
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