Mutation to Bax beyond the BH3 Domain Disrupts Interactions with Pro-survival Proteins and Promotes Apoptosis

Por Czabotar, Peter E., Lee, Erinna F., Thompson, Geoff V., Wardak, Ahmad Z., Fairlie, W. Douglas, Colman, Peter M.
Publicado em 2011

CD52 glycan binds the proinflammatory B box of HMGB1 to engage the Siglec-10 receptor and suppress human T cell function

Por Bandala-Sanchez, Esther, G. Bediaga, Naiara, Goddard-Borger, Ethan D., Ngui, Katrina, Naselli, Gaetano, Stone, Natalie L., Neale, Alana M., Pearce, Lesley A., Wardak, Ahmad, Czabotar, Peter, Haselhorst, Thomas, Maggioni, Andrea, Hartley-Tassell, Lauren A., Adams, Timothy E., Harrison, Leonard C.
Publicado no Proc Natl Acad Sci U S A (2018)

Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosis

Por Petrie, Emma J., Sandow, Jarrod J., Jacobsen, Annette V., Smith, Brian J., Griffin, Michael D. W., Lucet, Isabelle S., Dai, Weiwen, Young, Samuel N., Tanzer, Maria C., Wardak, Ahmad, Liang, Lung-Yu, Cowan, Angus D., Hildebrand, Joanne M., Kersten, Wilhelmus J. A., Lessene, Guillaume, Silke, John, Czabotar, Peter E., Webb, Andrew I., Murphy, James M.
Publicado no Nat Commun (2018)