Visualization and enrichment of live putative cancer stem cell populations following p53 inactivation or Bax deletion using non-toxic fluorescent dyes

Por Allen, Joshua E., Hart, Lori S., Dicker, David T., Wang, Wenge, El-Deiry, Wafik S.
Publicado em 2009

Off-target Lapatinib Activity Sensitizes Colon Cancer Cells through TRAIL Death Receptor Up-regulation

Por Dolloff, Nathan G., Mayes, Patrick A., Hart, Lori S., Dicker, David T., Humphreys, Robin, El-Deiry, Wafik S.
Publicado em 2011

High-Resolution Imaging and Antitumor Effects of GFP(+) Bone Marrow-Derived Cells Homing to Syngeneic Mouse Colon Tumors

Por Finnberg, Niklas K., Hart, Lori S., Dolloff, Nathan G., Rodgers, Zachary B., Dicker, David T., El-Deiry, Wafik S.
Publicado em 2011

The combination of 5-Fluorouracil plus p53 pathway restoration is associated with depletion of p53-deficient or mutant p53-expressing putative colon cancer stem cells

Por Huang, Catherine, Zhang, Xiang M., Tavaluc, Raluca T., Hart, Lori S., Dicker, David T., Wang, Wenge, El-Deiry, Wafik S.
Publicado no Cancer Biol Ther (2009)

Human colon cancer stem cells are enriched by insulin-like growth factor-1 and are sensitive to figitumumab

Por Hart, Lori S, Dolloff, Nathan G, Dicker, David T, Koumenis, Constantinos, Christensen, James G, Grimberg, Adda, El-Deiry, Wafik S
Publicado em 2011

The p53 target Plk2 interacts with TSC proteins impacting mTOR signaling, tumor growth and chemosensitivity under hypoxic conditions

Por Matthew, Elizabeth M., Hart, Lori S., Astrinidis, Aristotelis, Navaraj, Arunasalam, Dolloff, Nathan G., Dicker, David T., Henske, Elizabeth P., El-Deiry, Wafik S.
Publicado em 2009

The GCN2-ATF4 pathway is critical for tumour cell survival and proliferation in response to nutrient deprivation

Por Ye, Jiangbin, Kumanova, Monika, Hart, Lori S, Sloane, Kelly, Zhang, Haiyan, De Panis, Diego N, Bobrovnikova-Marjon, Ekaterina, Diehl, J Alan, Ron, David, Koumenis, Constantinos
Publicado em 2010

Transcriptomic profiling of 39 commonly-used neuroblastoma cell lines

Por Harenza, Jo Lynne, Diamond, Maura A., Adams, Rebecca N., Song, Michael M., Davidson, Heather L., Hart, Lori S., Dent, Maiah H., Fortina, Paolo, Reynolds, C. Patrick, Maris, John M.
Publicado no Sci Data (2017)

OSU-03012 Stimulates PKR-Like Endoplasmic Reticulum-Dependent Increases in 70-kDa Heat Shock Protein Expression, Attenuating Its Lethal Actions in Transformed Cells

Por Park, Margaret A., Yacoub, Adly, Rahmani, Mohammed, Zhang, Guo, Hart, Lori, Hagan, Michael P., Calderwood, Stuart K., Sherman, Michael Y., Koumenis, Costas, Spiegel, Sarah, Chen, Ching-Shih, Graf, Martin, Curiel, David T., Fisher, Paul B., Grant, Steven, Dent, Paul
Publicado em 2008

Overcoming hypoxia-induced apoptotic resistance through combinatorial inhibition of GSK-3β and CDK1

Por Mayes, Patrick A., Dolloff, Nathan G., Daniel, Colin J., Liu, J. Judy, Hart, Lori S., Kuribayashi, Kageaki, Allen, Joshua E., Jee, David I.H., Dorsey, Jay F., Liu, Yingqiu Y., Dicker, David T., Brown, J. Martin, Furth, Emma E., Klein, Peter S., Sears, Rosalie C., El-Deiry, Wafik S.
Publicado em 2011

Dual CDK4/CDK6 Inhibition Induces Cell Cycle Arrest and Senescence in Neuroblastoma

Por Rader, JulieAnn, Russell, Mike R., Hart, Lori S., Nakazawa, Michael S., Belcastro, Lili T., Martinez, Daniel, Li, Yimei, Carpenter, Erica L., Attiyeh, Edward F., Diskin, Sharon J., Kim, Sunkyu, Parasuraman, Sudha, Caponigro, Giordano, Schnepp, Robert W., Wood, Andrew C., Pawel, Bruce, Cole, Kristina A., Maris, John M.
Publicado em 2013

Dual ALK and CDK4/6 inhibition demonstrates synergy against neuroblastoma

Por Wood, Andrew C., Krytska, Kateryna, Ryles, Hannah, Infarinato, Nicole, Sano, Renata, Hansel, Theodore, Hart, Lori, King, Frederick J., Smith, Timothy R., Ainscow, Edward, Grandinetti, Kathryn B., Tuntland, Tove, Kim, Sunkyu, Caponigro, Giordano, He, You Qun, Krupa, Shiva, Li, Nanxin, Harris, Jennifer L., Mossé, Yaël P.
Publicado no Clin Cancer Res (2016)

Targeting ER stress–induced autophagy overcomes BRAF inhibitor resistance in melanoma

Por Ma, Xiao-Hong, Piao, Sheng-Fu, Dey, Souvik, Mcafee, Quentin, Karakousis, Giorgos, Villanueva, Jessie, Hart, Lori S., Levi, Samuel, Hu, Janice, Zhang, Gao, Lazova, Rossitza, Klump, Vincent, Pawelek, John M., Xu, Xiaowei, Xu, Wei, Schuchter, Lynn M., Davies, Michael A., Herlyn, Meenhard, Winkler, Jeffrey, Koumenis, Constantinos, Amaravadi, Ravi K.
Publicado em 2014

ER stress–mediated autophagy promotes Myc-dependent transformation and tumor growth

Por Hart, Lori S., Cunningham, John T., Datta, Tatini, Dey, Souvik, Tameire, Feven, Lehman, Stacey L., Qiu, Bo, Zhang, Haiyan, Cerniglia, George, Bi, Meixia, Li, Yan, Gao, Yan, Liu, Huayi, Li, Changhong, Maity, Amit, Thomas-Tikhonenko, Andrei, Perl, Alexander E., Koong, Albert, Fuchs, Serge Y., Diehl, J. Alan, Mills, Ian G., Ruggero, Davide, Koumenis, Constantinos
Publicado em 2012

Genetic predisposition to neuroblastoma mediated by a LMO1 super-enhancer polymorphism

Por Oldridge, Derek A., Wood, Andrew C., Weichert-Leahey, Nina, Crimmins, Ian, Sussman, Robyn, Winter, Cynthia, McDaniel, Lee D., Diamond, Maura, Hart, Lori S., Zhu, Shizhen, Durbin, Adam D., Abraham, Brian J., Anders, Lars, Tian, Lifeng, Zhang, Shile, Wei, Jun S., Khan, Javed, Bramlett, Kelli, Rahman, Nazneen, Capasso, Mario, Iolascon, Achille, Gerhard, Daniela S., Guidry Auvil, Jaime M., Young, Richard A., Hakonarson, Hakon, Diskin, Sharon J., Look, A. Thomas, Maris, John M.
Publicado no Nature (2015)

Relapsed neuroblastomas show frequent RAS-MAPK pathway mutations

Por Eleveld, Thomas F., Oldridge, Derek A., Bernard, Virginie, Koster, Jan, Daage, Leo Colmet, Diskin, Sharon J., Schild, Linda, Bentahar, Nadia Bessoltane, Bellini, Angela, Chicard, Mathieu, Lapouble, Eve, Combaret, Valérie, Legoix-Né, Patricia, Michon, Jean, Pugh, Trevor J., Hart, Lori S., Rader, JulieAnn, Attiyeh, Edward F., Wei, Jun S., Zhang, Shile, Naranjo, Arlene, Gastier-Foster, Julie M., Hogarty, Michael D., Asgharzadeh, Shahab, Smith, Malcolm A., Guidry Auvil, Jaime M., Watkins, Thomas B. K., Zwijnenburg, Danny A., Ebus, Marli E., van Sluis, Peter, Hakkert, Anne, van Wezel, Esther, van der Schoot, C. Ellen, Westerhout, Ellen M., Schulte, Johannes H., Tytgat, Godelieve A., Dolman, M. Emmy M., Janoueix-Lerosey, Isabelle, Gerhard, Daniela S., Caron, Huib N., Delattre, Olivier, Khan, Javed, Versteeg, Rogier, Schleiermacher, Gudrun, Molenaar, Jan J., Maris, John M.
Publicado no Nat Genet (2015)