Genomic profiling of pediatric acute myeloid leukemia reveals a changing mutational landscape from disease diagnosis to relapse

door Farrar, Jason E., Schuback, Heather L., Ries, Rhonda E., Wai, Daniel, Hampton, Oliver A., Trevino, Lisa R., Alonzo, Todd A., Guidry Auvil, Jaime M., Davidsen, Tanja M., Gesuwan, Patee, Hermida, Leandro, Muzny, Donna M., Dewal, Ninad, Rustagi, Navin, Lewis, Lora R., Gamis, Alan S., Wheeler, David A., Smith, Malcolm A., Gerhard, Daniela S., Meshinchi, Soheil
Gepubliceerd in Cancer Res (2016)

TCF21 hypermethylation in genetically quiescent clear cell sarcoma of the kidney

door Gooskens, Saskia L., Gadd, Samantha, Guidry Auvil, Jaime M., Gerhard, Daniela S., Khan, Javed, Patidar, Rajesh, Meerzaman, Daoud, Chen, Qing-Rong, Hsu, Chih Hao, Yan, Chunhua, Nguyen, Cu, Hu, Ying, Mullighan, Charles G., Ma, Jing, Jennings, Lawrence J., de Krijger, Ronald R., van den Heuvel-Eibrink, Marry M., Smith, Malcolm A., Ross, Nicole, Gastier-Foster, Julie M., Perlman, Elizabeth J.
Gepubliceerd in Oncotarget (2015)

MLLT1 YEATS domain mutations in clinically distinctive Favourable Histology Wilms tumours

door Perlman, Elizabeth J., Gadd, Samantha, Arold, Stefan T., Radhakrishnan, Anand, Gerhard, Daniela S., Jennings, Lawrence, Huff, Vicki, Guidry Auvil, Jaime M., Davidsen, Tanja M., Dome, Jeffrey S., Meerzaman, Daoud, Hsu, Chih Hao, Nguyen, Cu, Anderson, James, Ma, Yussanne, Mungall, Andrew J., Moore, Richard A., Marra, Marco A., Mullighan, Charles G., Ma, Jing, Wheeler, David A., Hampton, Oliver A., Gastier-Foster, Julie M., Ross, Nicole, Smith, Malcolm A.
Gepubliceerd in Nat Commun (2015)

CSF3R mutations have a high degree of overlap with CEBPA mutations in pediatric AML

door Maxson, Julia E., Ries, Rhonda E., Wang, Yi-Cheng, Gerbing, Robert B., Kolb, E. Anders, Thompson, Sarah L., Guidry Auvil, Jaime M., Marra, Marco A., Ma, Yussanne, Zong, Zusheng, Mungall, Andrew J., Moore, Richard, Long, William, Gesuwan, Patee, Davidsen, Tanja M., Hermida, Leandro C., Hughes, Seamus B., Farrar, Jason E., Radich, Jerald P., Smith, Malcolm A., Gerhard, Daniela S., Gamis, Alan S., Alonzo, Todd A., Meshinchi, Soheil
Gepubliceerd in Blood (2016)

Genetic predisposition to neuroblastoma mediated by a LMO1 super-enhancer polymorphism

door Oldridge, Derek A., Wood, Andrew C., Weichert-Leahey, Nina, Crimmins, Ian, Sussman, Robyn, Winter, Cynthia, McDaniel, Lee D., Diamond, Maura, Hart, Lori S., Zhu, Shizhen, Durbin, Adam D., Abraham, Brian J., Anders, Lars, Tian, Lifeng, Zhang, Shile, Wei, Jun S., Khan, Javed, Bramlett, Kelli, Rahman, Nazneen, Capasso, Mario, Iolascon, Achille, Gerhard, Daniela S., Guidry Auvil, Jaime M., Young, Richard A., Hakonarson, Hakon, Diskin, Sharon J., Look, A. Thomas, Maris, John M.
Gepubliceerd in Nature (2015)

A Children's Oncology Group and TARGET Initiative Exploring the Genetic Landscape of Wilms Tumor

door Gadd, Samantha, Huff, Vicki, Walz, Amy L., Ooms, Ariadne H.A.G., Armstrong, Amy E., Gerhard, Daniela S., Smith, Malcolm A., Guidry Auvil, Jaime M., Meerzaman, Daoud, Chen, Qing-Rong, Hsu, Chih Hao, Yan, Chunhua, Nguyen, Cu, Hu, Ying, Hermida, Leandro C., Davidsen, Tanja, Gesuwan, Patee, Ma, Yussanne, Zong, Zusheng, Mungall, Andrew J., Moore, Richard A., Marra, Marco A., Dome, Jeffrey S., Mullighan, Charles G., Ma, Jing, Wheeler, David A., Hampton, Oliver A., Ross, Nicole, Gastier-Foster, Julie M., Arold, Stefan T., Perlman, Elizabeth J.
Gepubliceerd in Nat Genet (2017)

Pan-cancer genome and transcriptome analyses of 1,699 pediatric leukemias and solid tumors

door Ma, Xiaotu, Liu, Yu, Liu, Yanling, Alexandrov, Ludmil B, Edmonson, Michael N., Gawad, Charles, Zhou, Xin, Li, Yongjin, Rusch, Michael C., Easton, John, Huether, Robert, Gonzalez-Pena, Veronica, Wilkinson, Mark R., Hermida, Leandro C., Davis, Sean, Sioson, Edgar, Pounds, Stanley, Cao, Xueyuan, Ries, Rhonda E., Wang, Zhaoming, Chen, Xiang, Dong, Li, Diskin, Sharon J., Smith, Malcolm A., Guidry Auvil, Jaime M., Meltzer, Paul S., Lau, Ching C., Perlman, Elizabeth J., Maris, John M., Meshinchi, Soheil, Hunger, Stephen P., Gerhard, Daniela S., Zhang, Jinghui
Gepubliceerd in Nature (2018)

Significance of TP53 Mutation in Wilms Tumors with Diffuse Anaplasia: A Report from the Children’s Oncology Group

door Ooms, Ariadne H.A.G., Gadd, Samantha, Gerhard, Daniela S., Smith, Malcolm A., Guidry Auvil, Jaime M., Meerzaman, Daoud, Chen, Qing-Rong, Hsu, Chih Hao, Yan, Chunhua, Nguyen, Cu, Hu, Ying, Ma, Yussanne, Zong, Zusheng, Mungall, Andrew J., Moore, Richard A., Marra, Marco A., Huff, Vicki, Dome, Jeffrey S., Chi, Yueh-Yun, Tian, Jing, Geller, James I., Mullighan, Charles G., Ma, Jing, Wheeler, David A., Hampton, Oliver A., Walz, Amy L., van den Heuvel-Eibrink, Marry M., de Krijger, Ronald R., Ross, Nicole, Gastier-Foster, Julie M., Perlman, Elizabeth J.
Gepubliceerd in Clin Cancer Res (2016)

Relapsed neuroblastomas show frequent RAS-MAPK pathway mutations

door Eleveld, Thomas F., Oldridge, Derek A., Bernard, Virginie, Koster, Jan, Daage, Leo Colmet, Diskin, Sharon J., Schild, Linda, Bentahar, Nadia Bessoltane, Bellini, Angela, Chicard, Mathieu, Lapouble, Eve, Combaret, Valérie, Legoix-Né, Patricia, Michon, Jean, Pugh, Trevor J., Hart, Lori S., Rader, JulieAnn, Attiyeh, Edward F., Wei, Jun S., Zhang, Shile, Naranjo, Arlene, Gastier-Foster, Julie M., Hogarty, Michael D., Asgharzadeh, Shahab, Smith, Malcolm A., Guidry Auvil, Jaime M., Watkins, Thomas B. K., Zwijnenburg, Danny A., Ebus, Marli E., van Sluis, Peter, Hakkert, Anne, van Wezel, Esther, van der Schoot, C. Ellen, Westerhout, Ellen M., Schulte, Johannes H., Tytgat, Godelieve A., Dolman, M. Emmy M., Janoueix-Lerosey, Isabelle, Gerhard, Daniela S., Caron, Huib N., Delattre, Olivier, Khan, Javed, Versteeg, Rogier, Schleiermacher, Gudrun, Molenaar, Jan J., Maris, John M.
Gepubliceerd in Nat Genet (2015)

The genetic basis and cell of origin of mixed phenotype acute leukaemia

door Alexander, Thomas B., Gu, Zhaohui, Iacobucci, Ilaria, Dickerson, Kirsten, Choi, John K., Xu, Beisi, Payne-Turner, Debbie, Yoshihara, Hiroki, Loh, Mignon L., Horan, John, Buldini, Barbara, Basso, Giuseppe, Elitzur, Sarah, de Haas, Valerie, Zwaan, C. Michel, Yeoh, Allen, Reinhardt, Dirk, Tomizawa, Daisuke, Kiyokawa, Nobutaka, Lammens, Tim, De Moerloose, Barbara, Catchpoole, Daniel, Hori, Hiroki, Moorman, Anthony, Moore, Andrew S., Hrusak, Ondrej, Meshinchi, Soheil, Orgel, Etan, Devidas, Meenakshi, Borowitz, Michael, Wood, Brent, Heerema, Nyla A., Carrol, Andrew, Yang, Yung-Li, Smith, Malcolm A., Davidsen, Tanja M., Hermida, Leandro C., Gesuwan, Patee, Marra, Marco A., Ma, Yussanne, Mungall, Andrew J., Moore, Richard A., Jones, Steven J. M., Valentine, Marcus, Janke, Laura J., Rubnitz, Jeffrey E., Pui, Ching-Hon, Ding, Liang, Liu, Yu, Zhang, Jinghui, Nichols, Kim E., Downing, James R., Cao, Xueyuan, Shi, Lei, Pounds, Stanley, Newman, Scott, Pei, Deqing, Guidry Auvil, Jaime M., Gerhard, Daniela S., Hunger, Stephen P., Inaba, Hiroto, Mullighan, Charles G.
Gepubliceerd in Nature (2018)