Significance of TP53 Mutation in Wilms Tumors with Diffuse Anaplasia: A Report from the Children’s Oncology Group

PURPOSE: To investigate the role and significance of TP53 mutation in diffusely anaplastic Wilms tumor (DAWT). EXPERIMENTAL DESIGN: All DAWTs registered on National Wilms Tumor Study-5 (n=118) with available samples were analyzed for TP53 mutations and copy loss. Integrative genomic analysis was per...

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Publicado no:Clin Cancer Res
Main Authors: Ooms, Ariadne H.A.G., Gadd, Samantha, Gerhard, Daniela S., Smith, Malcolm A., Guidry Auvil, Jaime M., Meerzaman, Daoud, Chen, Qing-Rong, Hsu, Chih Hao, Yan, Chunhua, Nguyen, Cu, Hu, Ying, Ma, Yussanne, Zong, Zusheng, Mungall, Andrew J., Moore, Richard A., Marra, Marco A., Huff, Vicki, Dome, Jeffrey S., Chi, Yueh-Yun, Tian, Jing, Geller, James I., Mullighan, Charles G., Ma, Jing, Wheeler, David A., Hampton, Oliver A., Walz, Amy L., van den Heuvel-Eibrink, Marry M., de Krijger, Ronald R., Ross, Nicole, Gastier-Foster, Julie M., Perlman, Elizabeth J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5290091/
https://ncbi.nlm.nih.gov/pubmed/27702824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-0985
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