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MLLT1 YEATS domain mutations in clinically distinctive Favourable Histology Wilms tumours

Wilms tumour is an embryonal tumour of childhood that closely resembles the developing kidney. Genomic changes responsible for the development of the majority of Wilms tumours remain largely unknown. Here we identify recurrent mutations within Wilms tumours that involve the highly conserved YEATS do...

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Publié dans:Nat Commun
Auteurs principaux: Perlman, Elizabeth J., Gadd, Samantha, Arold, Stefan T., Radhakrishnan, Anand, Gerhard, Daniela S., Jennings, Lawrence, Huff, Vicki, Guidry Auvil, Jaime M., Davidsen, Tanja M., Dome, Jeffrey S., Meerzaman, Daoud, Hsu, Chih Hao, Nguyen, Cu, Anderson, James, Ma, Yussanne, Mungall, Andrew J., Moore, Richard A., Marra, Marco A., Mullighan, Charles G., Ma, Jing, Wheeler, David A., Hampton, Oliver A., Gastier-Foster, Julie M., Ross, Nicole, Smith, Malcolm A.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686660/
https://ncbi.nlm.nih.gov/pubmed/26635203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10013
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