Human colon cancer stem cells are enriched by insulin-like growth factor-1 and are sensitive to figitumumab

Cancer stem cells (CSCs) are recognized as contributors to cancer progression and therapeutic resistance in liquid and solid malignancies. We analyzed a panel of human colon cancer cell lines for CSC populations by side population and aldehyde dehydrogenase activity. IGF-1 enriches these putative co...

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Detalhes bibliográficos
Main Authors: Hart, Lori S, Dolloff, Nathan G, Dicker, David T, Koumenis, Constantinos, Christensen, James G, Grimberg, Adda, El-Deiry, Wafik S
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322474/
https://ncbi.nlm.nih.gov/pubmed/21720213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.14.16418
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