Auto-Inhibition of Ets-1 Is Counteracted by DNA Binding Cooperativity with Core-Binding Factor α2

由 Goetz, Tamara L., Gu, Ting-Lei, Speck, Nancy A., Graves, Barbara J.
出版 2000

Auto-Inhibition and Partner Proteins, Core-Binding Factor β (CBFβ) and Ets-1, Modulate DNA Binding by CBFα2 (AML1)

由 Gu, Ting-Lei, Goetz, Tamara L., Graves, Barbara J., Speck, Nancy A.
出版 2000

Phosphorylation of the SSBP2 and ABL proteins by the ZNF198-FGFR1 fusion kinase seen in atypical myeloproliferative disorders as revealed by phosphopeptide-specific mass spectromet...

由 Kasyapa, Chitta, Gu, Ting-Lei, Natarajan, Lalitha, Polakiewicz, Roberto, Cowell, John K
出版 2009

Epidermal Growth Factor Stimulates RSK2 Activation through Activation of the MEK/ERK Pathway and Src-dependent Tyrosine Phosphorylation of RSK2 at Tyr-529

由 Kang, Sumin, Dong, Shaozhong, Guo, Ailan, Ruan, Hong, Lonial, Sagar, Khoury, Hanna Jean, Gu, Ting-Lei, Chen, Jing
出版 2007

14–3-3 integrates prosurvival signals mediated by the AKT and MAPK pathways in ZNF198-FGFR1–transformed hematopoietic cells

由 Dong, Shaozhong, Kang, Sumin, Gu, Ting-Lei, Kardar, Sean, Fu, Haian, Lonial, Sagar, Khoury, Hanna Jean, Khuri, Fadlo, Chen, Jing
出版 2007

Combination of rapamycin and protein tyrosine kinase (PTK) inhibitors for the treatment of leukemias caused by oncogenic PTKs

由 Mohi, M. Golam, Boulton, Christina, Gu, Ting-Lei, Sternberg, David W., Neuberg, Donna, Griffin, James D., Gilliland, D. Gary, Neel, Benjamin G.
出版 2004

Profiling Y561-Dependent and -Independent Substrates of CSF-1R in Epithelial Cells

由 Knowlton, Melodie L., Selfors, Laura M., Wrobel, Carolyn N., Gu, Ting-Lei, Ballif, Bryan A., Gygi, Steven P., Polakiewicz, Roberto, Brugge, Joan S.
出版 2010

Id1 is a common downstream target of oncogenic tyrosine kinases in leukemic cells

由 Tam, Winnie F., Gu, Ting-Lei, Chen, Jing, Lee, Benjamin H., Bullinger, Lars, Fröhling, Stefan, Wang, Andrew, Monti, Stefano, Golub, Todd R., Gilliland, D. Gary
出版 2008

Phospho-proteomic analysis of mantle cell lymphoma cells suggests a pro-survival role of B-cell receptor signaling

由 Pighi, Chiara, Gu, Ting-Lei, Dalai, Irene, Barbi, Stefano, Parolini, Claudia, Bertolaso, Anna, Pedron, Serena, Parisi, Alice, Ren, Jianmin, Cecconi, Daniela, Chilosi, Marco, Menestrina, Fabio, Zamò, Alberto
出版 2011

FGFR3 Activates RSK2 to Mediate Hematopoietic Transformation through Tyrosine Phosphorylation of RSK2 and Activation of the MEK/ERK Pathway

由 Kang, Sumin, Dong, Shaozhong, Gu, Ting-Lei, Guo, Ailan, Cohen, Michael S., Lonial, Sagar, Khoury, Hanna Jean, Fabbro, Doriano, Gary Gilliland, D., Leif Bergsagel, P., Taunton, Jack, Polakiewicz, Roberto D., Chen, Jing
出版 2007

JAK2T875N is a novel activating mutation that results in myeloproliferative disease with features of megakaryoblastic leukemia in a murine bone marrow transplantation model

由 Mercher, Thomas, Wernig, Gerlinde, Moore, Sandra A., Levine, Ross L., Gu, Ting-Lei, Fröhling, Stefan, Cullen, Dana, Polakiewicz, Roberto D., Bernard, Olivier A., Boggon, Titus J., Lee, Benjamin H., Gilliland, D. Gary
出版 2006

Tyrosine Phosphorylation of Lactate Dehydrogenase A Is Important for NADH/NAD(+) Redox Homeostasis in Cancer Cells

由 Fan, Jun, Hitosugi, Taro, Chung, Tae-Wook, Xie, Jianxin, Ge, Qingyuan, Gu, Ting-Lei, Polakiewicz, Roberto D., Chen, Georgia Z., Boggon, Titus J., Lonial, Sagar, Khuri, Fadlo R., Kang, Sumin, Chen, Jing
出版 2011

Disease mutations in RUNX1 and RUNX2 create nonfunctional, dominant-negative, or hypomorphic alleles

由 Matheny, Christina J, Speck, Maren E, Cushing, Patrick R, Zhou, Yunpeng, Corpora, Takeshi, Regan, Michael, Newman, Miki, Roudaia, Liya, Speck, Caroline L, Gu, Ting-Lei, Griffey, Stephen M, Bushweller, John H, Speck, Nancy A
出版 2007

Survey of Activated FLT3 Signaling in Leukemia

由 Gu, Ting-lei, Nardone, Julie, Wang, Yi, Loriaux, Marc, Villén, Judit, Beausoleil, Sean, Tucker, Meghan, Kornhauser, Jon, Ren, Jianmin, MacNeill, Joan, Gygi, Steven P., Druker, Brian J., Heinrich, Michael C., Rush, John, Polakiewicz, Roberto D.
出版 2011

Tyr-94 Phosphorylation Inhibits Pyruvate Dehydrogenase Phosphatase 1 and Promotes Tumor Growth

由 Shan, Changliang, Kang, Hee-Bum, Elf, Shannon, Xie, Jianxin, Gu, Ting-Lei, Aguiar, Mike, Lonning, Scott, Hitosugi, Taro, Chung, Tae-Wook, Arellano, Martha, Khoury, Hanna J., Shin, Dong M., Khuri, Fadlo R., Boggon, Titus J., Fan, Jun
出版 2014

A novel fusion of RBM6 to CSF1R in acute megakaryoblastic leukemia

由 Gu, Ting-lei, Mercher, Thomas, Tyner, Jeffrey W., Goss, Valerie L., Walters, Denise K., Cornejo, Melanie G., Reeves, Cynthia, Popova, Lana, Lee, Kimberly, Heinrich, Michael C., Rush, John, Daibata, Masanori, Miyoshi, Isao, Gilliland, D. Gary, Druker, Brian J., Polakiewicz, Roberto D.
出版 2007

Tyrosine phosphorylation of mitochondrial pyruvate dehydrogenase kinase 1 is important for cancer metabolism

由 Hitosugi, Taro, Fan, Jun, Chung, Tae-Wook, Lythgoe, Katherine, Wang, Xu, Xie, Jianxin, Ge, Qingyuan, Gu, Ting-Lei, Polakiewicz, Roberto D., Roesel, Johannes L., Chen, Zhuo (Georgia), Boggon, Titus J., Lonial, Sagar, Fu, Haian, Khuri, Fadlo R., Kang, Sumin, Chen, Jing
出版 2011

The Prometastatic Ribosomal S6 Kinase 2-cAMP Response Element-binding Protein (RSK2-CREB) Signaling Pathway Up-regulates the Actin-binding Protein Fascin-1 to Promote Tumor Metasta...

由 Li, Dan, Jin, Lingtao, Alesi, Gina N., Kim, Young-Mee, Fan, Jun, Seo, Jae Ho, Wang, Dongsheng, Tucker, Meghan, Gu, Ting-Lei, Lee, Benjamin H., Taunton, Jack, Magliocca, Kelly R., Chen, Zhuo G., Shin, Dong M., Khuri, Fadlo R., Kang, Sumin
出版 2013

Tyr-301 Phosphorylation Inhibits Pyruvate Dehydrogenase by Blocking Substrate Binding and Promotes the Warburg Effect

由 Fan, Jun, Kang, Hee-Bum, Shan, Changliang, Elf, Shannon, Lin, Ruiting, Xie, Jianxin, Gu, Ting-Lei, Aguiar, Mike, Lonning, Scott, Chung, Tae-Wook, Arellano, Martha, Khoury, Hanna J., Shin, Dong M., Khuri, Fadlo R., Boggon, Titus J., Kang, Sumin, Chen, Jing
出版 2014

Fibroblast Growth Factor Receptor 3 Associates with and Tyrosine Phosphorylates p90 RSK2, Leading to RSK2 Activation That Mediates Hematopoietic Transformation

由 Kang, Sumin, Elf, Shannon, Dong, Shaozhong, Hitosugi, Taro, Lythgoe, Katherine, Guo, Ailan, Ruan, Hong, Lonial, Sagar, Khoury, Hanna J., Williams, Ifor R., Lee, Benjamin H., Roesel, Johannes L., Karsenty, Gerard, Hanauer, André, Taunton, Jack, Boggon, Titus J., Gu, Ting-Lei, Chen, Jing
出版 2009