Utilizing native fluorescence imaging, modeling and simulation to examine pharmacokinetics and therapeutic regimen of a novel anticancer prodrug

Tekijä Wang, Jing-Hung, Endsley, Aaron N., Green, Carol E., Matin, A. C.
Julkaisussa BMC Cancer (2016)

Pharmacokinetics and Metabolism of 4R-Cembranoid

Tekijä Vélez-Carrasco, Wanda, Green, Carol E., Catz, Paul, Furimsky, Anna, O’Loughlin, Kathleen, Eterović, Vesna A., Ferchmin, P. A.
Julkaisussa PLoS One (2015)

Improved oral bioavailability in rats of SR13668, a novel anti-cancer agent

Tekijä Green, Carol E., Swezey, Robert, Bakke, James, Shinn, Walter, Furimsky, Anna, Bejugam, Naveen, Shankar, Gita N., Jong, Ling, Kapetanovic, Izet M.
Julkaistu 2010

Novel Brain-Penetrating Oxime Acetylcholinesterase Reactivators Attenuate Organophosphate-Induced Neuropathology in the Rat Hippocampus

Tekijä Dail, Mary B, Leach, Charles A, Meek, Edward C, Olivier, Alicia K, Pringle, Ronald B, Green, Carol E, Chambers, Janice E
Julkaisussa Toxicol Sci (2019)

Efficacy of the GluK1/AMPA Receptor Antagonist LY293558 against Seizures and Neuropathology in a Soman-Exposure Model without Pretreatment and its Pharmacokinetics after Intramuscu...

Tekijä Apland, James P., Aroniadou-Anderjaska, Vassiliki, Figueiredo, Taiza H., Green, Carol E., Swezey, Robert, Yang, Chun, Qashu, Felicia, Braga, Maria F. M.
Julkaistu 2013

The Stereoselective Sulfate Conjugation of 4-Methoxyfenoterol Stereoisomers by Sulfotransferase Enzymes

Tekijä Iyer, Lalitha V., Ramamoorthy, Anuradha, Rutkowska, Ewelina, Furimsky, Anna M., Tang, Liang, Catz, Paul, Green, Carol E., Jozwiak, Krzysztof, Wainer, Irving W.
Julkaisussa Chirality (2012)

Metabolism, Pharmacokinetics, Tissue Distribution, and Stability Studies of the Prodrug Analog of an Anti-Hepatitis B Virus Dinucleoside Phosphorothioate

Tekijä Coughlin, John E., Pandey, Rajendra K., Padmanabhan, Seetharamaiyer, O'Loughlin, Kathleen G., Marquis, Judith, Green, Carol E., Mirsalis, Jon C., Iyer, Radhakrishnan P.
Julkaistu 2012

Pharmacokinetics and Metabolism of (R,R)-Methoxyfenoterol in Rat

Tekijä Siluk, Danuta, Mager, Donald E., Kim, Hee Seung, Wang, Yan, Furimsky, Anna M., Ta, Amy, Iyer, Lalitha V., Green, Carol E., Wainer, Irving W.
Julkaistu 2010

(R,S)-Ketamine metabolites (R,S)-norketamine and (2S,6S)-hydroxynorketamine increase the mammalian target of rapamycin (mTOR) function

Tekijä Paul, Rajib K., Singh, Nagendra S., Khadeer, Mohammed, Moaddel, Ruin, Sanghvi, Mitesh, Green, Carol E, O’Loughlin, Kathleen, Torjman, Marc C., Bernier, Michel, Wainer, Irving W.
Julkaistu 2014

A parallel chiral-achiral liquid chromatographic method for the determination of the stereoisomers of ketamine and ketamine metabolites in the plasma and urine of patients with com...

Tekijä Moaddel, Ruin, Venkata, Swarajya Lakshmi Vattem, Tanga, Mary J., Bupp, James E., Green, Carol E., Iyer, Lalitha, Furimsky, Anna, Goldberg, Michael E., Torjman, Marc C., Wainer, Irving W.
Julkaistu 2010

Identification of (+)-Erythro-Mefloquine as an Active Enantiomer with Greater Efficacy than Mefloquine against Mycobacterium avium Infection in Mice

Tekijä Bermudez, Luiz E., Inderlied, Clark B., Kolonoski, Peter, Chee, Christopher B., Aralar, Priscilla, Petrofsky, Mary, Parman, Toufan, Green, Carol E., Lewin, Anita H., Ellis, William Y., Young, Lowell S.
Julkaistu 2012

Efficacy of Tilorone Dihydrochloride against Ebola Virus Infection

Tekijä Ekins, Sean, Lingerfelt, Mary A., Comer, Jason E., Freiberg, Alexander N., Mirsalis, Jon C., O'Loughlin, Kathleen, Harutyunyan, Anush, McFarlane, Claire, Green, Carol E., Madrid, Peter B.
Julkaisussa Antimicrob Agents Chemother (2018)

Orally Bioavailable Anti-HBV Dinucleotide Acyloxyalkyl Prodrugs

Tekijä Coughlin, John E., Padmanabhan, Seetharamaiyer, Zhang, Guangrong, Kirk, Cassandra J., Govardhan, Chandrika P., Korba, Brent E., O'Loughlin, Kathleen, Green, Carol E., Mirsalis, Jon, Morrey, John D., Iyer, Radhakrishnan P.
Julkaistu 2010

Toxicogenomics and Metabolomics of Pentamethylchromanol (PMCol)-Induced Hepatotoxicity

Tekijä Parman, Toufan, Bunin, Deborah I., Ng, Hanna H., McDunn, Jonathan E., Wulff, Jacob E., Wang, Abraham, Swezey, Robert, Rasay, Laura, Fairchild, David G., Kapetanovic, Izet M., Green, Carol E.
Julkaistu 2011

Development of a New Generation of 4-Aminoquinoline Antimalarial Compounds Using Predictive Pharmacokinetic and Toxicology Models

Tekijä Ray, Sunetra, Madrid, Peter B., Catz, Paul, LeValley, Susanna E., Furniss, Michael J., Rausch, Linda L., Guy, R. Kiplin, DeRisi, Joseph L., Iyer, Lalitha V., Green, Carol E., Mirsalis, Jon C.
Julkaistu 2010

Discovery and Optimization of Benzotriazine Di-N-Oxides Targeting Replicating and Non-replicating Mycobacterium tuberculosis

Tekijä Chopra, Sidharth, Koolpe, Gary A., Tambo-ong, Arlyn A., Matsuyama, Karen N., Ryan, Kenneth J., Tran, Tran B., Doppalapudi, Rupa S., Riccio, Edward S., Iyer, Lalitha V., Green, Carol E., Wan, Baojie, Franzblau, Scott G., Madrid, Peter B.
Julkaistu 2012

In Vitro and In Vivo Activity of Amiodarone Against Ebola Virus

Tekijä Dyall, Julie, Johnson, Joshua C, Hart, Brit J, Postnikova, Elena, Cong, Yu, Zhou, Huanying, Gerhardt, Dawn M, Michelotti, Julia, Honko, Anna N, Kern, Steven, DeWald, Lisa Evans, O’Loughlin, Kathleen G, Green, Carol E, Mirsalis, Jon C, Bennett, Richard S, Olinger, Gene G, Jahrling, Peter B, Hensley, Lisa E
Julkaisussa J Infect Dis (2018)

In Vivo Activity of Amodiaquine against Ebola Virus Infection

Tekijä DeWald, Lisa Evans, Johnson, Joshua C., Gerhardt, Dawn M., Torzewski, Lisa M., Postnikova, Elena, Honko, Anna N., Janosko, Krisztina, Huzella, Louis, Dowling, William E., Eakin, Ann E., Osborn, Blaire L., Gahagen, Janet, Tang, Liang, Green, Carol E., Mirsalis, Jon C., Holbrook, Michael R., Jahrling, Peter B., Dyall, Julie, Hensley, Lisa E.
Julkaisussa Sci Rep (2019)

Evaluation of Arylimidamides DB1955 and DB1960 as Candidates against Visceral Leishmaniasis and Chagas' Disease: In Vivo Efficacy, Acute Toxicity, Pharmacokinetics, and Toxicology...

Tekijä Zhu, Xiaohua, Liu, Qiang, Yang, Sihyung, Parman, Toufan, Green, Carol E., Mirsalis, Jon C., de Nazaré Correia Soeiro, Maria, Mello de Souza, Elen, da Silva, Cristiane França, da Gama Jaen Batista, Denise, Stephens, Chad E., Banerjee, Moloy, Farahat, Abdelbasset A., Munde, Manoj, Wilson, W. David, Boykin, David W., Wang, Michael Zhuo, Werbovetz, Karl A.
Julkaistu 2012

A Systematic Screen of FDA-Approved Drugs for Inhibitors of Biological Threat Agents

Tekijä Madrid, Peter B., Chopra, Sidharth, Manger, Ian D., Gilfillan, Lynne, Keepers, Tiffany R., Shurtleff, Amy C., Green, Carol E., Iyer, Lalitha V., Dilks, Holli Hutcheson, Davey, Robert A., Kolokoltsov, Andrey A., Carrion, Ricardo, Patterson, Jean L., Bavari, Sina, Panchal, Rekha G., Warren, Travis K., Wells, Jay B., Moos, Walter H., Burke, RaeLyn L., Tanga, Mary J.
Julkaistu 2013