Efficacy of Tilorone Dihydrochloride against Ebola Virus Infection

Tilorone dihydrochloride (tilorone) is a small-molecule, orally bioavailable drug that is used clinically as an antiviral outside the United States. A machine-learning model trained on anti-Ebola virus (EBOV) screening data previously identified tilorone as a potent in vitro EBOV inhibitor, making i...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Ekins, Sean, Lingerfelt, Mary A., Comer, Jason E., Freiberg, Alexander N., Mirsalis, Jon C., O'Loughlin, Kathleen, Harutyunyan, Anush, McFarlane, Claire, Green, Carol E., Madrid, Peter B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5786809/
https://ncbi.nlm.nih.gov/pubmed/29133569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01711-17
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