The Stereoselective Sulfate Conjugation of 4-Methoxyfenoterol Stereoisomers by Sulfotransferase Enzymes

The presystemic sulfate conjugation of the stereoisomers of 4-methoxyfenoterol, (R,R)-MF, (S,S)-MF, (R,S)-MF, and (S,R)-MF, was investigated using commercially available human intestinal S9 fractions, a mixture of sulfotransferase (SULT) enzymes. The results indicate that the sulfation was stereospe...

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Publicat a:Chirality
Autors principals: Iyer, Lalitha V., Ramamoorthy, Anuradha, Rutkowska, Ewelina, Furimsky, Anna M., Tang, Liang, Catz, Paul, Green, Carol E., Jozwiak, Krzysztof, Wainer, Irving W.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6131691/
https://ncbi.nlm.nih.gov/pubmed/22744891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chir.22072
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