Evaluation of Arylimidamides DB1955 and DB1960 as Candidates against Visceral Leishmaniasis and Chagas' Disease: In Vivo Efficacy, Acute Toxicity, Pharmacokinetics, and Toxicology Studies

Arylimidamides (AIAs) have shown outstanding in vitro potency against intracellular kinetoplastid parasites, and the AIA 2,5-bis[2-(2-propoxy)-4-(2-pyridylimino)aminophenyl]furan dihydrochloride (DB766) displayed good in vivo efficacy in rodent models of visceral leishmaniasis (VL) and Chagas'...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Zhu, Xiaohua, Liu, Qiang, Yang, Sihyung, Parman, Toufan, Green, Carol E., Mirsalis, Jon C., de Nazaré Correia Soeiro, Maria, Mello de Souza, Elen, da Silva, Cristiane França, da Gama Jaen Batista, Denise, Stephens, Chad E., Banerjee, Moloy, Farahat, Abdelbasset A., Munde, Manoj, Wilson, W. David, Boykin, David W., Wang, Michael Zhuo, Werbovetz, Karl A.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Microbiology 2012
Θέματα:
Experimental Therapeutics
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393454/
https://ncbi.nlm.nih.gov/pubmed/22508306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.06404-11
Ετικέτες: Προσθήκη ετικέτας
Δεν υπάρχουν, Καταχωρήστε ετικέτα πρώτοι!

Παρόμοια τεκμήρια