Arylimidamide DB766, a Potential Chemotherapeutic Candidate for Chagas' Disease Treatment

Chagas' disease, a neglected tropical illness for which current therapy is unsatisfactory, is caused by the intracellular parasite Trypanosoma cruzi. The goal of this work is to investigate the in vitro and in vivo effects of the arylimidamide (AIA) DB766 against T. cruzi. This arylimidamide ex...

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Main Authors: Batista, Denise da Gama Jaén, Batista, Marcos Meuser, Oliveira, Gabriel Melo de, Amaral, Patrícia Borges do, Lannes-Vieira, Joseli, Britto, Constança Carvalho, Junqueira, Angela, Lima, Marli Maria, Romanha, Alvaro José, Sales Junior, Policarpo Ademar, Stephens, Chad E., Boykin, David W., Soeiro, Maria de Nazaré Correia
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2010
Fag:
Experimental Therapeutics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897275/
https://ncbi.nlm.nih.gov/pubmed/20457822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01617-09
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