Targeting Individual GPCRs with Redesigned Nonvisual Arrestins

by Gimenez, Luis E., Vishnivetskiy, Sergey A., Gurevich, Vsevolod V.
Published in Handb Exp Pharmacol (2014)

Crystal structure of arrestin-3 reveals the basis of the difference in receptor binding between two non-visual subtypes

by Zhan, Xuanzhi, Gimenez, Luis E., Gurevich, Vsevolod V., Spiller, Benjamin W.
Published 2011

Manipulation of Very Few Receptor Discriminator Residues Greatly Enhances Receptor Specificity of Non-visual Arrestins

by Gimenez, Luis E., Vishnivetskiy, Sergey A., Baameur, Faiza, Gurevich, Vsevolod V.
Published 2012

Salmeterol Efficacy and Bias in the Activation and Kinase-Mediated Desensitization of β2-Adrenergic Receptors

by Gimenez, Luis E., Baameur, Faiza, Vayttaden, Sharat J., Clark, Richard B.
Published in Mol Pharmacol (2015)

Arrestin-3 binds the MAP kinase JNK3α2 via multiple sites on both domains

by Zhan, Xuanzhi, Perez, Alejandro, Gimenez, Luis E., Vishnivetskiy, Sergey A., Gurevich, Vsevolod V.
Published 2014

Mutations in arrestin-3 differentially affect binding to neuropeptide Y receptor subtypes

by Gimenez, Luis E., Babilon, Stefanie, Wanka, Lizzy, Beck-Sickinger, Annette G., Gurevich, Vsevolod V.
Published 2014

Ligand-induced Internalization and Recycling of the Human Neuropeptide Y(2) Receptor Is Regulated by Its Carboxyl-terminal Tail

by Walther, Cornelia, Nagel, Stefanie, Gimenez, Luis E., Mörl, Karin, Gurevich, Vsevolod V., Beck-Sickinger, Annette G.
Published 2010

Role of Receptor-attached Phosphates in Binding of Visual and Non-visual Arrestins to G Protein-coupled Receptors

by Gimenez, Luis E., Kook, Seunghyi, Vishnivetskiy, Sergey A., Ahmed, M. Rafiuddin, Gurevich, Eugenia V., Gurevich, Vsevolod V.
Published 2012

Silent Scaffolds: INHIBITION OF c-Jun N-TERMINAL KINASE 3 ACTIVITY IN CELL BY DOMINANT-NEGATIVE ARRESTIN-3 MUTANT

by Breitman, Maya, Kook, Seunghyi, Gimenez, Luis E., Lizama, Britney N., Palazzo, Maria C., Gurevich, Eugenia V., Gurevich, Vsevolod V.
Published 2012

Few Residues within an Extensive Binding Interface Drive Receptor Interaction and Determine the Specificity of Arrestin Proteins

by Vishnivetskiy, Sergey A., Gimenez, Luis E., Francis, Derek J., Hanson, Susan M., Hubbell, Wayne L., Klug, Candice S., Gurevich, Vsevolod V.
Published 2011

The GPCR accessory protein MRAP2 regulates both biased signaling and constitutive activity of the ghrelin receptor GHSR1a

by Rouault, Alix A. J., Rosselli-Murai, Luciana K., Hernandez, Ciria C., Gimenez, Luis E., Tall, Gregory G., Sebag, Julien A.
Published in Sci Signal (2020)

Membrane orientation and oligomerization of the melanocortin receptor accessory protein 2

by Chen, Valerie, Bruno, Antonio E., Britt, Laura L., Hernandez, Ciria C., Gimenez, Luis E., Peisley, Alys, Cone, Roger D., Millhauser, Glenn L.
Published in J Biol Chem (2020)

60 YEARS OF POMC: Regulation of feeding and energy homeostasis by α-MSH

by Anderson, Erica J P, Çakir, Isin, Carrington, Sheridan J, Cone, Roger D, Ghamari-Langroudi, Masoud, Gillyard, Taneisha, Gimenez, Luis E, Litt, Michael J
Published in J Mol Endocrinol (2016)

Modulation of Methuselah Expression Targeted to Drosophila Insulin-producing Cells Extends Life and Enhances Oxidative Stress Resistance

by Gimenez, Luis E. D., Ghildyal, Parakashtha, Fischer, Kathleen E., Hu, Hongxiang, Ja, William W., Eaton, Benjamin A., Wu, Yimin, Austad, Steven N., Ranjan, Ravi
Published 2012

Autoantibodies Enhance Agonist Action and Binding to Cardiac Muscarinic Receptors in Chronic Chagas’ Disease

by Hernández, Ciria C., Nascimento, José H., Chaves, Elen A., Costa, Patrícia C., Masuda, Masako O., Kurtenbach, Eleonora, Campos de Carvalho, Antônio C., Giménez, Luis E.
Published 2008

A Role for an Hsp70 Nucleotide Exchange Factor in the Regulation of Synaptic Vesicle Endocytosis

by Morgan, Jennifer R., Jiang, Jianwen, Oliphint, Paul A., Jin, Suping, Gimenez, Luis E., Busch, David J., Foldes, Andrea E., Zhuo, Yue, Sousa, Rui, Lafer, Eileen M.
Published 2013

A G Protein-biased Designer G Protein-coupled Receptor Useful for Studying the Physiological Relevance of G(q/11)-dependent Signaling Pathways

by Hu, Jianxin, Stern, Matthew, Gimenez, Luis E., Wanka, Lizzy, Zhu, Lu, Rossi, Mario, Meister, Jaroslawna, Inoue, Asuka, Beck-Sickinger, Annette G., Gurevich, Vsevolod V., Wess, Jürgen
Published in J Biol Chem (2016)

Peptide Modifications Differentially Alter G Protein-Coupled Receptor Internalization and Signaling Bias()

by Mäde, Veronika, Babilon, Stefanie, Jolly, Navjeet, Wanka, Lizzy, Bellmann-Sickert, Kathrin, Diaz Gimenez, Luis E., Mörl, Karin, Cox, Helen M., Gurevich, Vsevolod V., Beck-Sickinger, Annette G.
Published in Angew Chem Int Ed Engl (2014)

Structure of the Hsp110:Hsc70 Nucleotide Exchange Machine

by Schuermann, Jonathan P., Jiang, Jianwen, Cuellar, Jorge, Llorca, Oscar, Wang, Liping, Gimenez, Luis E., Jin, Suping, Taylor, Alexander B., Demeler, Borries, Morano, Kevin A., Hart, P. John, Valpuesta, Jose M., Lafer, Eileen M., Sousa, Rui
Published 2008

Determination of the melanocortin-4 receptor structure identifies Ca(2+) as a cofactor for ligand binding

by Yu, Jing, Gimenez, Luis E., Hernandez, Ciria C., Wu, Yiran, Wein, Ariel H., Han, Gye Won, McClary, Kyle, Mittal, Sanraj R., Burdsall, Kylie, Stauch, Benjamin, Wu, Lijie, Stevens, Sophia N., Peisley, Alys, Williams, Savannah Y., Chen, Valerie, Millhauser, Glenn L., Zhao, Suwen, Cone, Roger D., Stevens, Raymond C.
Published in Science (2020)