A G Protein-biased Designer G Protein-coupled Receptor Useful for Studying the Physiological Relevance of G(q/11)-dependent Signaling Pathways

Designer receptors exclusively activated by a designer drug (DREADDs) are clozapine-N-oxide-sensitive designer G protein-coupled receptors (GPCRs) that have emerged as powerful novel chemogenetic tools to study the physiological relevance of GPCR signaling pathways in specific cell types or tissues....

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Hu, Jianxin, Stern, Matthew, Gimenez, Luis E., Wanka, Lizzy, Zhu, Lu, Rossi, Mario, Meister, Jaroslawna, Inoue, Asuka, Beck-Sickinger, Annette G., Gurevich, Vsevolod V., Wess, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824988/
https://ncbi.nlm.nih.gov/pubmed/26851281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.702282
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