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Ligand-induced Internalization and Recycling of the Human Neuropeptide Y(2) Receptor Is Regulated by Its Carboxyl-terminal Tail

Agonist-induced internalization of G protein-coupled receptors plays an important role in signal regulation. The underlying mechanisms of the internalization of the human neuropeptide Y(2) receptor (hY(2)R), as well as its desensitization, endocytosis, and resensitization are mainly unknown. In the...

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Detalhes bibliográficos
Main Authors: Walther, Cornelia, Nagel, Stefanie, Gimenez, Luis E., Mörl, Karin, Gurevich, Vsevolod V., Beck-Sickinger, Annette G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3009885/
https://ncbi.nlm.nih.gov/pubmed/20959467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.162156
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