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Mutations in arrestin-3 differentially affect binding to neuropeptide Y receptor subtypes

Based on the identification of residues that determine receptor selectivity in arrestins and the phylogenetic analysis of the arrestin (arr) family, we introduced fifteen mutations of receptor-discriminator residues in arr-3, which were identified previously using mutagenesis, in vitro binding, and...

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Detalhes bibliográficos
Main Authors: Gimenez, Luis E., Babilon, Stefanie, Wanka, Lizzy, Beck-Sickinger, Annette G., Gurevich, Vsevolod V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4033671/
https://ncbi.nlm.nih.gov/pubmed/24686081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2014.03.019
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