A G Protein-biased Designer G Protein-coupled Receptor Useful for Studying the Physiological Relevance of G(q/11)-dependent Signaling Pathways

Designer receptors exclusively activated by a designer drug (DREADDs) are clozapine-N-oxide-sensitive designer G protein-coupled receptors (GPCRs) that have emerged as powerful novel chemogenetic tools to study the physiological relevance of GPCR signaling pathways in specific cell types or tissues....

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Hu, Jianxin, Stern, Matthew, Gimenez, Luis E., Wanka, Lizzy, Zhu, Lu, Rossi, Mario, Meister, Jaroslawna, Inoue, Asuka, Beck-Sickinger, Annette G., Gurevich, Vsevolod V., Wess, Jürgen
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2016
Schlagworte:
Signal Transduction
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824988/
https://ncbi.nlm.nih.gov/pubmed/26851281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.702282
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge