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Role of Receptor-attached Phosphates in Binding of Visual and Non-visual Arrestins to G Protein-coupled Receptors

Arrestins are a small family of proteins that regulate G protein-coupled receptors (GPCRs). Arrestins specifically bind to phosphorylated active receptors, terminating G protein coupling, targeting receptors to endocytic vesicles, and initiating G protein-independent signaling. The interaction of rh...

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Detalhes bibliográficos
Main Authors: Gimenez, Luis E., Kook, Seunghyi, Vishnivetskiy, Sergey A., Ahmed, M. Rafiuddin, Gurevich, Eugenia V., Gurevich, Vsevolod V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308753/
https://ncbi.nlm.nih.gov/pubmed/22275358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.311803
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