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The structural basis of arrestin-mediated regulation of G-protein-coupled receptors
The 4 mammalian arrestins serve as almost universal regulators of the largest known family of signaling proteins, G-protein-coupled receptors (GPCRs). Arrestins terminate receptor interactions with G proteins, redirect the signaling to a variety of alternative pathways, and orchestrate receptor inte...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2006
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2562282/ https://ncbi.nlm.nih.gov/pubmed/16460808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2005.09.008 |
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