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The structural basis of arrestin-mediated regulation of G-protein-coupled receptors

The 4 mammalian arrestins serve as almost universal regulators of the largest known family of signaling proteins, G-protein-coupled receptors (GPCRs). Arrestins terminate receptor interactions with G proteins, redirect the signaling to a variety of alternative pathways, and orchestrate receptor inte...

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Autori principali: Gurevich, Vsevolod V., Gurevich, Eugenia V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2562282/
https://ncbi.nlm.nih.gov/pubmed/16460808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2005.09.008
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