Učitavanje...
The Origin and Evolution of G Protein-Coupled Receptor Kinases
G protein-coupled receptor (GPCR) kinases (GRKs) play key role in homologous desensitization of GPCRs. GRKs phosphorylate activated receptors, promoting high affinity binding of arrestins, which precludes G protein coupling. Direct binding to active GPCRs activates GRKs, so that they selectively pho...
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| Glavni autori: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science
2012
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3307776/ https://ncbi.nlm.nih.gov/pubmed/22442725 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033806 |
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