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Silent Scaffolds: INHIBITION OF c-Jun N-TERMINAL KINASE 3 ACTIVITY IN CELL BY DOMINANT-NEGATIVE ARRESTIN-3 MUTANT

We established a new in vivo arrestin-3-JNK3 interaction assay based on bioluminescence resonance energy transfer (BRET) between JNK3-luciferase and Venus-arrestins. We tested the ability of WT arrestin-3 and its 3A mutant that readily binds β2-adrenergic receptors as well as two mutants impaired in...

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Autores principales: Breitman, Maya, Kook, Seunghyi, Gimenez, Luis E., Lizama, Britney N., Palazzo, Maria C., Gurevich, Eugenia V., Gurevich, Vsevolod V.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366000/
https://ncbi.nlm.nih.gov/pubmed/22523077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.358192
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