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Identification of Arrestin-3-specific Residues Necessary for JNK3 Kinase Activation
Arrestins bind active phosphorylated G protein-coupled receptors, blocking G protein activation and channeling the signaling to G protein-independent pathways. Free arrestin-3 and receptor-bound arrestin-3 scaffold the ASK1-MKK4-JNK3 module, promoting JNK3 phosphorylation, whereas highly homologous...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3151035/ https://ncbi.nlm.nih.gov/pubmed/21715332 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.260448 |
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