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Modulation of Methuselah Expression Targeted to Drosophila Insulin-producing Cells Extends Life and Enhances Oxidative Stress Resistance

Ubiquitously reduced signaling via Methuselah (MTH), a G-protein coupled receptor (GPCR) required for neurosecretion, has previously been reported to extend life and enhance stress resistance in flies. Whether these effects are due to reduced MTH signaling only in specific tissue(s) and through with...

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Bibliografske podrobnosti
Main Authors: Gimenez, Luis E. D., Ghildyal, Parakashtha, Fischer, Kathleen E., Hu, Hongxiang, Ja, William W., Eaton, Benjamin A., Wu, Yimin, Austad, Steven N., Ranjan, Ravi
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552032/
https://ncbi.nlm.nih.gov/pubmed/23121290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12027
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