Increased uncoupling protein (UCP) activity in Drosophila insulin-producing neurons attenuates insulin signaling and extends lifespan

To understand the role of mitochondrial uncoupling protein (UCP) in regulating insulin signaling and glucose homeostasis, we created transgenicDrosophila lines with targeted UCP expression in insulin producing cells (IPCs). Increased UCP activity in IPCs results in decreased steady state Ca(2+) leve...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Main Authors: Fridell, Yih-Woei C., Hoh, Melissa, Kréneisz, Orsolya, Hosier, Suzanne, Chang, Chengyi, Scantling, Dane, Mulkey, Daniel K., Helfand, Stephen L.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Impact Journals LLC 2009
Ábhair:
Priority Research Paper
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830081/
https://ncbi.nlm.nih.gov/pubmed/20195385
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla