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Glucose increases activity and Ca(2+) in Adult Drosophila Insulin Producing Cells

We sought to understand mechanisms underlying glucose sensing in Drosophila melanogaster. We found that adult insulin producing cells (IPCs) respond to glucose and glibenclamide with a burst-like pattern of activity. Under control conditions IPCs have a resting membrane potential of −62 ± 4 mV. In r...

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Detalhes bibliográficos
Main Authors: Kréneisz, Orsolya, Chen, Xinnian, Fridell, Yih-Woei C., Mulkey, Daniel K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075590/
https://ncbi.nlm.nih.gov/pubmed/20890228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/WNR.0b013e3283409200
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