Indy gene variation in natural populations confers fitness advantage and life span extension through transposon insertion

Por Zhu, Chen-Tseh, Chang, Chengyi, Reenan, Robert A., Helfand, Stephen L.
Publicado em 2014

Dominant-negative Dmp53 extends life span through the dTOR pathway in D. melanogaster

Por Bauer, Johannes H., Chang, Chengyi, Bae, Gina, Morris, Siti Nur Sarah, Helfand, Stephen L.
Publicado em 2010

Comparative transcriptional profiling identifies takeout as a gene that regulates life span

Por Bauer, Johannes, Antosh, Michael, Chang, Chengyi, Schorl, Christoph, Kolli, Santharam, Neretti, Nicola, Helfand, Stephen L.
Publicado em 2010

dSir2 and Dmp53 interact to mediate aspects of CR-dependent life span extension in D. melanogaster

Por Bauer, Johannes H., Morris, Siti Nur Sarah, Chang, Chengyi, Flatt*, Thomas, Wood, Jason G., Helfand, Stephen L.
Publicado em 2008

Expression of dominant-negative Dmp53 in the adult fly brain inhibits insulin signaling

Por Bauer, Johannes H., Chang, Chengyi, Morris, Siti Nur Sarah, Hozier, Suzanne, Andersen, Sandra, Waitzman, Joshua S., Helfand, Stephen L.
Publicado em 2007

Long-lived Indy and calorie restriction interact to extend life span

Por Wang, Pei-Yu, Neretti, Nicola, Whitaker, Rachel, Hosier, Suzanne, Chang, Chengyi, Lu, Daniel, Rogina, Blanka, Helfand, Stephen L.
Publicado em 2009

Comparative transcriptional pathway bioinformatic analysis of dietary restriction, Sir2, p53 and resveratrol life span extension in Drosophila

Por Antosh, Michael, Whitaker, Rachel, Kroll, Adam, Hosier, Suzanne, Chang, Chengyi, Bauer, Johannes, Cooper, Leon, Neretti, Nicola, Helfand, Stephen L
Publicado em 2011

Increased uncoupling protein (UCP) activity in Drosophila insulin-producing neurons attenuates insulin signaling and extends lifespan

Por Fridell, Yih-Woei C., Hoh, Melissa, Kréneisz, Orsolya, Hosier, Suzanne, Chang, Chengyi, Scantling, Dane, Mulkey, Daniel K., Helfand, Stephen L.
Publicado em 2009

A somatic piRNA pathway in the Drosophila fat body ensures metabolic homeostasis and normal lifespan

Por Jones, Brian C., Wood, Jason G., Chang, Chengyi, Tam, Austin D., Franklin, Michael J., Siegel, Emily R., Helfand, Stephen L.
Publicado no Nat Commun (2016)

Chromatin remodeling in the aging genome of Drosophila

Por Wood, Jason G., Hillenmeyer, Sara, Lawrence, Charles, Chang, Chengyi, Hosier, Suzanne, Lightfoot, Will, Mukherjee, Eric, Jiang, Nan, Schorl, Christoph, Brodsky, Alexander S., Neretti, Nicola, Helfand, Stephen L.
Publicado em 2010

Chromatin-modifying genetic interventions suppress age-associated transposable element activation and extend life span in Drosophila

Por Wood, Jason G., Jones, Brian C., Jiang, Nan, Chang, Chengyi, Hosier, Suzanne, Wickremesinghe, Priyan, Garcia, Meyrolin, Hartnett, Davis A., Burhenn, Lucas, Neretti, Nicola, Helfand, Stephen L.
Publicado no Proc Natl Acad Sci U S A (2016)