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Involvement of Drosophila Uncoupling Protein 5 in Metabolism and Aging
A novel uncoupling protein, UCP5, has recently been characterized as a functional mitochondrial uncoupler in Drosophila. Here we demonstrate that UCP5 knockout (UCP5KO) flies are highly sensitive to starvation stress, a phenotype that can be reversed by ectopic neuronal expression of UCP5. UCP5KO fl...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Copyright © 2006 by the Genetics Society of America
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1456275/ https://ncbi.nlm.nih.gov/pubmed/16387864 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.105.053389 |
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