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Involvement of Drosophila Uncoupling Protein 5 in Metabolism and Aging

A novel uncoupling protein, UCP5, has recently been characterized as a functional mitochondrial uncoupler in Drosophila. Here we demonstrate that UCP5 knockout (UCP5KO) flies are highly sensitive to starvation stress, a phenotype that can be reversed by ectopic neuronal expression of UCP5. UCP5KO fl...

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書誌詳細
主要な著者: Sánchez-Blanco, Adolfo, Fridell, Yih-Woei C., Helfand, Stephen L.
フォーマット: Artigo
言語:Inglês
出版事項: Copyright © 2006 by the Genetics Society of America 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456275/
https://ncbi.nlm.nih.gov/pubmed/16387864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.105.053389
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