A proposal: Evolution of PCNA's role as a marker of newly replicated DNA

Por Georgescu, Roxana, Langston, Lance, O'Donnell, Mike
Publicado no DNA Repair (Amst) (2015)

A solution to release twisted DNA during chromosome replication by coupled DNA polymerases

Por Kurth, Isabel, Georgescu, Roxana E., O’Donnell, Mike
Publicado em 2013

Combining conformational flexibility and continuum electrostatics for calculating pK(a)s in proteins.

Por Georgescu, Roxana E, Alexov, Emil G, Gunner, Marilyn R
Publicado em 2002

Single-molecule analysis of the E. coli replisome and use of clamps to bypass replication barriers

Por Georgescu, Roxana E., Yao, Nina Y., O’Donnell, Mike
Publicado em 2010

Single-molecule studies reveal the function of a third polymerase in the replisome

Por Georgescu, Roxana E, Kurth, Isabel, O'Donnell, Mike E
Publicado em 2011

A peptide switch regulates DNA polymerase processivity

Por López de Saro, Francisco J., Georgescu, Roxana E., O'Donnell, Mike
Publicado em 2003

Protein trafficking on sliding clamps.

Por López de Saro, Francisco, Georgescu, Roxana E, Leu, Frank, O'Donnell, Mike
Publicado em 2004

Single-molecule analysis reveals that the lagging strand increases replisome processivity but slows replication fork progression

Por Yao, Nina Y., Georgescu, Roxana E., Finkelstein, Jeff, O'Donnell, Michael E.
Publicado em 2009

Replisome mechanics: lagging strand events that influence speed and processivity

Por Georgescu, Roxana E., Yao, Nina, Indiani, Chiara, Yurieva, Olga, O'Donnell, Mike E.
Publicado em 2014

The DnaC helicase loader is a dual ATP/ADP switch protein

Por Davey, Megan J., Fang, Linhua, McInerney, Peter, Georgescu, Roxana E., O’Donnell, Mike
Publicado em 2002

Competitive processivity-clamp usage by DNA polymerases during DNA replication and repair

Por López de Saro, Francisco J., Georgescu, Roxana E., Goodman, Myron F., O’Donnell, Mike
Publicado em 2003

Architecture of the Saccharomyces cerevisiae Replisome

Por Bai, Lin, Yuan, Zuanning, Sun, Jingchuan, Georgescu, Roxana, O’Donnell, Michael E., Li, Huilin
Publicado no Adv Exp Med Biol (2017)

Mechanism of polymerase collision release from sliding clamps on the lagging strand

Por Georgescu, Roxana E, Kurth, Isabel, Yao, Nina Y, Stewart, Jelena, Yurieva, Olga, O'Donnell, Mike
Publicado em 2009

STRUCTURE OF A SLIDING CLAMP ON DNA

Por Georgescu, Roxana E., Kim, Seung-Sup, Yurieva, Olga, Kuriyan, John, Kong, Xiang-Peng, O’Donnell, Mike
Publicado em 2008

Structure of a small-molecule inhibitor of a DNA polymerase sliding clamp

Por Georgescu, Roxana E., Yurieva, Olga, Kim, Seung-Sup, Kuriyan, John, Kong, Xiang-Peng, O'Donnell, Mike
Publicado em 2008

Structure of the eukaryotic replicative CMG helicase and pumpjack motion

Por Yuan, Zuanning, Bai, Lin, Sun, Jingchuan, Georgescu, Roxana, Liu, Jun, O’Donnell, Michael E., Li, Huilin
Publicado no Nat Struct Mol Biol (2016)

The Architecture of a Eukaryotic Replisome

Por Sun, Jingchuan, Shi, Yi, Georgescu, Roxana E., Yuan, Zuanning, Chait, Brian T., Li, Huilin, O’Donnell, Michael E.
Publicado no Nat Struct Mol Biol (2015)

Mechanism of asymmetric polymerase assembly at the eukaryotic replication fork

Por Georgescu, Roxana E, Langston, Lance, Yao, Nina Y, Yurieva, Olga, Zhang, Dan, Finkelstein, Jeff, Agarwal, Tani, O’Donnell, Mike E
Publicado no Nat Struct Mol Biol (2014)

CMG helicase and DNA polymerase ε form a functional 15-subunit holoenzyme for eukaryotic leading-strand DNA replication

Por Langston, Lance D., Zhang, Dan, Yurieva, Olga, Georgescu, Roxana E., Finkelstein, Jeff, Yao, Nina Y., Indiani, Chiara, O’Donnell, Mike E.
Publicado em 2014

Reconstitution of a eukaryotic replisome reveals suppression mechanisms that define leading/lagging strand operation

Por Georgescu, Roxana E, Schauer, Grant D, Yao, Nina Y, Langston, Lance D, Yurieva, Olga, Zhang, Dan, Finkelstein, Jeff, O'Donnell, Mike E
Publicado no eLife (2015)