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The Architecture of a Eukaryotic Replisome
At the eukaryotic DNA replication fork, it is widely believed that the Cdc45-Mcm2-7-GINS (CMG) helicase leads the way in front to unwind DNA, and that DNA polymerases (Pol) trail behind the helicase. Here we use single particle electron microscopy to directly image a replisome. Contrary to expectati...
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| Publicado no: | Nat Struct Mol Biol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4849863/ https://ncbi.nlm.nih.gov/pubmed/26524492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3113 |
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