The Architecture of a Eukaryotic Replisome

At the eukaryotic DNA replication fork, it is widely believed that the Cdc45-Mcm2-7-GINS (CMG) helicase leads the way in front to unwind DNA, and that DNA polymerases (Pol) trail behind the helicase. Here we use single particle electron microscopy to directly image a replisome. Contrary to expectati...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Struct Mol Biol
Prif Awduron: Sun, Jingchuan, Shi, Yi, Georgescu, Roxana E., Yuan, Zuanning, Chait, Brian T., Li, Huilin, O’Donnell, Michael E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4849863/
https://ncbi.nlm.nih.gov/pubmed/26524492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3113
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg