Structure of eukaryotic CMG helicase at a replication fork and implications to replisome architecture and origin initiation

The eukaryotic CMG (Cdc45, Mcm2–7, GINS) helicase consists of the Mcm2–7 hexameric ring along with five accessory factors. The Mcm2–7 heterohexamer, like other hexameric helicases, is shaped like a ring with two tiers, an N-tier ring composed of the N-terminal domains, and a C-tier of C-terminal dom...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Georgescu, Roxana, Yuan, Zuanning, Bai, Lin, de Luna Almeida Santos, Ruda, Sun, Jingchuan, Zhang, Dan, Yurieva, Olga, Li, Huilin, O’Donnell, Michael E.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5293012/
https://ncbi.nlm.nih.gov/pubmed/28096349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1620500114
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados